Biofuel is renewable, clean and enviroment friendly. However the cost to extract it from biomass are very high and economically inefficient compare to fossil fuel. Energy company did not have any choice to choose fossil fuels eventhough fossil fuels are major culprit of global warming and increasing global greenhouse gases. But is not the omega of biofuels research.
By indentify additional enzyme that can digest cellulose efficiently can help to develop biofuels in industrial scale.Living in cow rumen, the uncultured microorganisms is highly effective at degrading plant cell wall. Hess et al. (p. 463) used metagenomics and single-genome sequencing to assemble draft genomes from microbes adhering to rumen-incubated switchgrass to identify nearly 28,000 genes related to known biomass-degrading families. Ninety candidate carbohydrate-degrading enzymes were synthesized and their activity analyzed against 10 different substrates, including the biofuel crops miscanthus and switchgrass. The data set greatly expands the repertoire of full-length genes available for use in industrial biotechnology.
Within 28000 genes we must narrow-down to more specific group in order to find what the exactly the important addtional enzymes. In order to translate those genes, must involved a lot of molecular technique and of course involves many parties. Molecular Biology knowlegde can't stand alone without intergrated with other field such as biochemistery and microbiology.
With knowledge of genetic integrated with biochemistry in determining biological or enzyme pathway to degrade the cellulose plus microbiologist to understanding the behaviour of microbes, we can find alternatives way to produced biofuel that are very effective and econimically effective. Come on Bioligist, Lets work together for bettter future.
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